Our blogs and videos choice: mitochondrial dna

Ancestry DNA Testing| Information | homeDNAdirect.com.au Blog

Ancestry DNA testing: A General Overview Posted on | August 13, 2010 | No Comments There are many reasons to carry out ancestry DNA testing; ancestry testing can tell you so much about your history and ancestors, that which you cannot find out any other way than by doing such a test. The test will link you to your deep and far back geogenetic roots going back thousands and thousands of years. Moreover, it can help all the more those who are clueless or simply wish to know more about their ancestral origins. To trace you ancestral origins, you will be provided with an ancestry testing kit. [more...]

Date: 2010-08-13 10:50:48

Blog posts (128) | Videos (16)

Cat DNA Can Aid in Criminal Investigations | easyDNA Blog

If you have ever inquired about a hair DNA test or know some of the basics of DNA you may know that DNA is found throughout nucleated cells in the body. Since hairs are simply made up of protein then we know that there is no nuclear DNA in hair. The same applies for cats- there is no nuclear DNA in cat hair. However, cat hair and human hair contain what is known as MtDNA (mitochondrial DNA) and this, like nuclear DNA, is unique to each of us. Cat DNA convicts murderer A body was found in a grave on Prince Edward Island, Canada. Police investigators identified the body as belonging to Shirley [more...]

Date: 2010-05-20 08:24:39

Gene Sequencing: DNA analysis

Not everyone can properly and correctly analyze the DNA. Apartyears of study devoted to knowledge of DNA, DNA analysts to go through years of experience and practice in laboratories and practice of DNA testing and analysis in order to analyze the DNA and how it works. The training of DNA analysts understanding of sophisticated tools and machines developed for DNA analysis. proper management and use of these devices would make them more efficient in the pursuit of DNA to be analyzed correctly. Most of the DNA consists of 23Pairs of chromosomes, mitochondrial DNA inherited from the mother, and [more...]

Date: 2010-09-22 05:00:00

Conservation of Plant Species in DNA Banks | Plant Biotech Blog ...

Although the MBG describes its activity as ‘DNA Banking’, there is no evidence on its website that MBG banks extracted DNA samples.  It is a collection of samples of plant material stored at -20°C, suitable for DNA extraction.  Voucher specimens for these samples are deposited at the MBG or other institutions.  The material is provided to researchers against an agreement for molecular studies but not for commercial purposes such as bioprospecting, or screening for genes of interest in agricultural research. DNA Bank Brazilian Flora Species The Bank at the Rio de Janeiro Botanical [more...]

Date: 2008-09-24 17:57:16

cryptogon.com » New Book Looks at Connection Between Mobile ...

An Australian team led by a fellow named John Aitkin believes that cellphone radiation weakens the ability of the sperm cell to swim because it’s affecting mitochondrial DNA (mitochondria are basically the engines of the cell). Very similar work was done at one of the top research institutions in Turkey, and in Poland, Hungary and India. Disconnect: The Truth About Cell Phone Radiation, What the Industry Has Done to Hide It, and How to Protect Your Family by Devra Davis Via: Salon: Strange how hard it is to remember a time before cellphones. Mobile phones have changed the way we spend our [more...]

Date: 2010-10-12 08:40:08

Martin Luther King traces DNA to Sierra Leone | Sierra Express Media

The DNA testing of both King and Garvey, which were revealed at the African Ancestry dinner and program at the Hyatt Regency Atlanta, Centennial Ballroom, established that King and Garvey’s maternal ancestry originated in Sierra Leone hundreds of years ago before they were forcefully taken to the United States as slaves. Garvey and King were among several other African Americans whose DNA results were revealed at the special dinner session on Sunday night at the just concluded Africa Policy Forum: A Vision For The 21st Century in Atlanta, Georgia. Speaking with this press immediately [more...]

Date: 2010-04-27 07:00:00

Human remains identified as those of Alice Donovan | SCNOW

The remains werefirst sent to a lab at the University of South Carolina for possible mitochondrial DNA extraction and testing. But forensic scientists at the state crime lab weren’t able to pull enough DNA from the skeletal remains for a positive identification. The Horry County Police Department since had been in contact with the Health Science Center at the University of North Texas, where the remains — along with DNA swabs taken during the Jan. 27 search from Gilchrist and Warner — were sent for additional testing, Horry County Police Sgt. Robert Kegler said. Most of the search for [more...]

Date: 2009-07-24 21:51:37

Lactic acidemia in the pathogenesis of mice carrying mitochondrial ...

Lactic acidemia is one manifestation of the mitochondrial diseases caused by pathogenic mutant mitochondrial DNA (mtDNA). However, little is known about its chronic effects in the progression of mitochondrial disease phenotypes. To obtain experimental evidence on this point, we used trans-mitochondrial model mice (mito-mice) heteroplasmic for wild-type and deleted mtDNA (ΔmtDNA). Mito-mice carrying predominantly ΔmtDNA showed mitochondrial respiration defects and the resultant disease phenotypes, including lactic acidemia; they also showed a decrease in mitochondrial biogenesis regulated by [more...]

Date: 2010-06-21 16:20:22

ISPUB - What's There In Our Genes? A Case For A More Inclusive And ...

We need better reviews, use of both qualitative and quantitative data as well as much more rigorous testing of newer and older models. Only then may we make full use of this large amount of data that has already been collected over the years. What we have described here, for now, presents part of the picture seen from the Indian subcontinent as an example. However, this situation is probably true of other parts of the world as well, perhaps even those areas where it has been assumed that the data is likely to be homogenous. Thus, even biological anthropologists need to add new sensitivities [more...]

Date: 2010-10-07 04:39:48

The Real Eve Streaming

The Real Eve Streaming. Movie Title: The Real Eve Average customer review: The Real Eve is available for streaming or downloading. Click Here to Stream or Download The Real Eve I highly recommend this work!!! Two-thumbs up. It’s possibly the best allotment of work on the genealogy and evolution of humans I have seen in my lifetime. By researching and explaining the migration of novel humans from Africa throughout the rest of the world the research completely challenges our whole conception of Speed since it proves that we are all related somehow — every single person on the planet can [more...]

Date: 2010-10-05 14:40:23

Tracing Birth Parents by Testing Your DNA

The tests can even distinguish a half sibling from a full sibling. If you followed my advice and used both Family Finder and Relative Finder, you can test the suspected relative with whichever test costs less. Both should do a good job of confirming a close relationship. NOTE: Do not count on a Y-DNA test for close relationship testing. While Y-DNA matches definitely share a common paternal ancestor, the test can only tie you to a family, not to any one person. Mitochondrial DNA? Both men and women can also take a mitochondrial (mtDNA) test that follows the maternal line. But learning [more...]

Date: 2010-05-05 14:19:14

The Journey of Man: A Genetic Odyssey

A very nice book if one is interested in understanding how DNA analysis is being used to trace human migration and from where it started. Would like more substance. There is no in-depth explanation of mitochondrial DNA dating, Y-chromosome dating, etc. More red meat than Seven Daughters of Eve for sure! Does this book have. Interesting. I thought it was a good book- and being a molecular biologist who is familiar with the worlds advanced knowledge of genetics, I am quite comfortable with my African origins and the obvious fact that we (meaning all races) are all extremely similar. Fascinating [more...]

Date: 2010-05-23 10:41:42

Links of London almost entirely

Links of London sale Six years ago the term "genetic genealogy" was meaningless, says Bennett Greenspan, head of Family Tree DNA, a testing firm with 52,000 customers. "Now the interest is huge." As individuals track down their personal family narratives, population geneticists are seeking to tell the larger story of humankind. Our Links of London Black Friendship Bracelet recent common ancestorsa genetic "Adam" and "Eve"have been traced back to Africa, and other intriguing forebears are being discovered all over the map. One group of scientists recently found that 40 percent of the world’s [more...]

Date: 2010-10-07 02:55:30

DNA test strengthens Alanta child killings case

The FBI report said this: “Wayne Williams cannot be excluded as the source of the hair.” The finding is not ironclad. Because the hairs were incomplete, the type of testing, called mitochondrial DNA, can trace only the maternal line. Only with nucleic DNA testing, which includes paternal lineage, could the results be absolutely conclusive. When CNN showed the DNA results to victim Baltazar’s stepmother, Sheila Baltazar, she said, “Without a shadow of a doubt, I really in my heart believe Wayne Williams killed Patrick Baltazar.” Williams not only has denied he killed Patrick [more...]

Date: 2010-09-04 22:12:37

Mitochondrial DNA Genealogy

The mitochondrial DNA genealogy is the study of a person’s mother’s family line of maternal ancestors. This DNA is passed down from mother to each of her children exactly as she has it, with no mutations, except in the very rare instances. Because of the traditions in our society of the wife taking her husband’s last name, a surname genealogy trace of the female line of the family tree is more difficult. On the flip side, since this DNA strand is more stable than the Y DNA, more conclusive results can be determined for the testing of it. The mt-DNA is sometimes referred to as the Full [more...]

Date: 2010-10-05 09:25:26

DNA test strengthens Atlanta child killings case | Akira Daily News

Because the hairs were incomplete, the type of testing, called mitochondrial DNA, can trace only the maternal line. Only with nucleic DNA testing, which includes paternal lineage, could the results be absolutely conclusive. When CNN showed the DNA results to victim Baltazar’s stepmother, Sheila Baltazar, she said, “Without a shadow of a doubt, I really in my heart believe Wayne Williams killed Patrick Baltazar.” Williams not only has denied he killed Patrick Baltazar, but has said he never met the boy. Yet testimony at trial established various fibers found on the Baltazar clothing [more...]

Date: 2010-06-09 14:12:26

Mitochondrial DNA rearrangement associated with fertility ...

Comparison of the mitochondrial DNA restriction patterns of CMS-Sprite, the three fertile revertants, and the five restored lines revealed loss of a 6.0-kilobase (kb) Pst I fragment in all restored and revertant lines. Southern hybridizations with a 1.3-kb BamHI clone, internal to the 6.0-kb Pst I fragment, as a probe revealed two configurations of 6.0-kb homologous sequences in the sterile cytoplasm; one of the configurations was lost upon reversion or restoration. Mitochondrial DNA rearrangement has thus been observed upon restoration by a nuclear restorer gene in this CMS [more...]

Date: 2010-09-29 13:30:31

The Aging Brain - Annual Review of Pathology: Mechanisms of ...

... long distances in the brain. Hence, this neuronal population is also quite vulnerable to mitochondrial dysfunction. Two major sites of mitochondrial damage during aging are the respiratory chain enzymes and mitochondrial DNA (63). .... These observations suggest that impaired mitochondrial function can lead to nuclear DNA damage that may, in turn, reduce the expression of nuclear-encoded mitochondrial genes, setting up a deleterious feedback loop in the aging brain. [more...]

Date: 2008-01-30 23:28:43

Can DNA Tests Reveal Nationality? » Scienceline

The Borders Agency is primarily using two types of DNA tests: mitochondrial DNA tests, which examine the genetic information stored in a cellular structure called a mitochondrion, and what are called Y-line tests, which look at markers on the Y-chromosome passed from father to son. These tests have been widely used to examine people’s ancestral heritage. Since certain genetic variations are typical in certain areas, geneticists can use an individual’s DNA to estimate where their ancestors came from. But when this technique is used to look at someone’s nationality rather than the origin [more...]

Date: 2009-12-30 06:05:09

UC Berkeley DNA testing goes before state committee | Berkeleyside

Inquiries by CRG with the California Department of Health have revealed that the School of Public Health is not licensed to perform this kind of clinical laboratory testing under California law. Furthermore, according to the California Department of Health, Professor Jasper Rine is not a medical doctor licensed to order and perform clinical laboratory tests as required by the Department. Therefore, as currently described, the program may be in violation of California’s public health laws and regulations. Finally, CRG has discovered that Jasper Rine received a four year grant for $1 million [more...]

Date: 2010-08-11 19:19:51

Forensic DNA Analysis – What is Mitochondrial DNA?

Mitochondrial DNA can also be found in some tissues where nuclear DNA normally does not exist. For instance, dead cellular debris can be found in human hair. However, the only thing that is living in human hair the follicle, [more...]

Date: 2010-08-22 08:31:49

race/history/evolution notes: Highly divergent ancient hominin ...

Svante Paabo assumes "some new creature" "carried this mitochondrial genome out of Africa about a million years", as do most commentators. It strikes me that a multiregionalist explanation is as consistent if not more consistent with the evidence at hand. If we entertain the possibility that "African Eve" ultimately descends from Eurasian Homo erectus, we don't need to posit some unknown intermediate "out of Africa" event. Reference: Johannes Krause, Qiaomei Fu, Jeffrey M. Good, Bence Viola, Michael V. Shunkov, Anatoli P. Derevianko & Svante Pääbo. The complete mitochondrial DNA genome of [more...]

Date: 2010-03-25 03:22:00

DNA findings point to royal roots in African nations

Holland attributes his success to GeneTree, a Utah-based DNA testing service that came up with the Cameroon connection. But GeneTree's chief scientific officer, geneticist Scott Woodward, said Williams' case was far from unusual. "This isn't our home run," Woodward told me. "It takes a lot of regular work. But what did do was give us some nice clues and hints about where he should concentrate his efforts. Should he be looking in Cameroon, or should he be looking in Nigeria? That makes a big difference." In fact, previous genetic tests had indeed suggested that Holland's [more...]

Date: 2010-09-09 14:14:55

Y Chromosome tinkering

The other women's mitochondrial lines died out when either they had only sons (who would not pass on the mitochondrial DNA) or no children at all, leaving only hers. Same for the Y chromosome Adam, an ancestor of all men alive today who lived 60,000 years ago. He was not the only man alive, but the other men's lines all ended across the 60,000 years when they either had only daughters (who do not have a Y chromosome) or no children at all. This was further sped up by Genghis Khan, a Mongolian ruler who had a lot of children, who in turn had many more children. He is the ancestor of 16 million [more...]

Date: 2010-10-08 11:23:00

DNA Testing Ordered For Texas Man Executed in 2000

The Legal Defenders * High Rates of Success * Free and Confidential Consultation We are following a very interesting case in Texas.  Claude "Butch" Jones was the last person executed in Texas in 2000, which set a national record.  He had been convicted of the robbery and murder of a liquor store owner.  Jones had always maintained his innocence.  A hair fragment, which had been recovered from the counter of the liquor store, was the only physical evidence connecting Jones to the murder.  The testimony at his trial was that a microscopic examination of the hair fragment "matched" Jones' [more...]

Date: 2010-06-16 14:46:00

Raciality.com - and Brutality: Haplogroup H is the most common ...

In human mitochondrial genetics, Haplogroup H is a human mitochondrial DNA (mtDNA) haplogroup. Haplogroup H is a descendant of haplogroup HV. The Cambridge Reference Sequence (CRS), the human mitochondrial sequence to which all other sequences are compared, belongs to haplogroup H. Haplogroup H is the most common mtDNA haplogroup in Europe. About one half of Europeans are of mtDNA haplogroup H. The haplogroup is also common in North Africa and the Middle East. The majority of the European populations have an overall haplogroup H frequency of 40%–50%. Frequencies decrease in the southeast of [more...]

Date: 2009-04-13 15:58:00

A Girl In Mexico In The 1930s Went Into A Mineshaft And Found An ...

However, Mr Pye believed the samples were contaminated and had it re-tested by a different lab in 2004, which managed to recover mitochondrial DNA, but not nuclear DNA. This meant either the nuclear DNA was too degraded to recover, or the DNA from the father was too different from that of a human to be detected. This year, the skull was tested by an ultra high-tech genetic lab, which was unable to match part of the nuclear DNA samples to any other samples in the enormous genetic database at the US National Institutes of Health. Mr Pye is convinced it is only a matter of time before the [more...]

Date: 2010-10-04 18:17:19

Oditous's 23andme results - ForumBiodiversity.com » Anthropology ...

Got the results today Apparently i'm triracial, most similar with north europeans but cluster with berber Mozabites from africa Maternal and paternal lineages are not really surprising but still kind of unexpected on a subregional scale. Need to do more research on that. At the moment i'm most interested in the 3% Asian admixture. Does anyone know if there's a way to delve deeper into this, even if it's only a small percentage? I'm supposing it's big enough to rule out any possible mistake by 23&me? According to regional breakdown central asians would be the source of my asian [more...]

Date: 2010-01-27 13:29:15

Raciality.com - and Brutality: The Molecular Dissection of mtDNA ...

These maps show where the samples were taken for the study ( First Map ) - Second map shows the frequency or density of mtDNA haplogroup H in Europe. This is the "Helen" descent in the "Seven Daughters of Eve" book. Some excerpts : Complete sequencing of 62 mitochondrial DNAs (mtDNAs) belonging (or very closely related) to haplogroup H revealed that this mtDNA haplogroup—by far the most common in Europe—is subdivided into numerous subhaplogroups, with at least 15 of them (H1–H15) identifiable by characteristic mutations. All the haplogroup H mtDNAs found in 5,743 subjects from 43 [more...]

Date: 2009-04-13 22:28:00

Interview with Arun Kumar: Genographic Postdoc, India - Genographica

I have worked with state of the art DNA technologies like Taqman assays, Fragment Analysis and DNA sequencing and have gained a true global experience working with on the Genographic team. Everyday brings a new learning experience! GP: Wait a minute, for those of us that aren't scientists, what is an assay? Arun Kumar: An assay is a way to genotype a specific mutation within DNA. In other words, it is an experiment that helps to identify a specific nucleotide with Y chromosome or mitochondrial DNA. This mutation will define the ancestral or derived state which will help to identify the [more...]

Date: 2010-10-07 19:07:51

Tribal DNA Test How Different American Indian Tribes Have ...

Generations of American families in the United States sometimes believe that they have Native American blood in their genes. If traditional research methods fail to produce any information, a DNA test may be just the thing you should try.Here are some things you should know about DNA testing and how it may determine which American Indian tribe you belong to:1. A DNA test can determine two of an individual’s many lineages.One way to determine a lineage is the mtDNA or the mitochondrial DNA test, which traces the genetic lineage along the maternal line. The Y chromosome DNA test, on the other [more...]

Date: 2010-09-10 07:46:18

Mitochondrial DNA Testing Also known as explained maternal DNA

As a test of nuclear DNA Mitochondrial DNA testing is done byDNA samples of indigenous membership is claret from a sample with a swab or audacity, boldness news regulation adopted broom used. These samples are again beatific abroad for laboratories that do DNA testing and test results of mitochondrial turnaround. Mitochondrial DNA testing is set in a Cardinal of the affidavit – is native to authorize a common ancestor absolute auxiliary mother of the family, can also beacclimated in the ancestor of DNA tests to analyze the ancestor of the mother or polemical in DNA testing. In 1980, Dr. [more...]

Date: 2010-10-09 09:31:52

Dienekes' Anthropology Blog: Dissection of mtDNA Haplogroup H

mtDNA haplogroup H is very widely distributed in Caucasoid populations reaching very high frequencies. This new study suggests that two subhaplogroups H1 and H3 diffused from the Franco-Cantabrian refuge after the Last Glacial Maximum. Am. J. Hum. Genet., 75:000, 2004 The Molecular Dissection of mtDNA Haplogroup H Confirms That the Franco-Cantabrian Glacial Refuge Was a Major Source for the European Gene Pool Alessandro Achilli et al. Complete sequencing of 62 mitochondrial DNAs (mtDNAs) belonging (or very closely related) to haplogroup H revealed that this mtDNA haplogroup—by [more...]

Date: 2004-09-22 00:55:00

Human Ancestry And Migration

The Genographic Project, launched in April 2005, is a five-year genetic anthropology study that aims to map historical human migration patterns by collecting and analyzing DNA samples from hundreds of thousands of people from around the world. Field researchers at 10 regional centers around the world collect DNA samples from indigenous populations. The company also sells self-testing kits: for US$100 anyone in the world can order a self-testing kit from which a mouth scraping (buccal swab) is obtained, analyzed and the DNA information placed on an Internet accessible database. The genetic [more...]

Date: 2010-08-04 01:49:04

Come celebrate Y-DNA testing at GeneTree

We are so excited to have Y-DNA testing at GeneTree! To help you get excited, we are offering you $20 off a Y-DNA test of your choice. We are offering the Y-33 and Y-46 tests. $20 off Y-DNA Testing at GeneTree Become a part of the largest and most diverse databases of linked DNA and family history information in the world. Come explore your past with a Y-DNA test for $20 off!* *Prices begin at a market low $149 with an additional $20 off if you order by 12 pm MST on August 31. Additional discounts are available for those who have already had a mitochondrial DNA test through [more...]

Date: 2008-08-07 22:16:54

dna sequencing

DNA sequencing reactions all use a primer to initiate DNA synthesis.  A Quicktime animation of how dideoxy nucleotides are incorporated into DNA in sequencing reactions. Nucleic acid sequence This sequence is written as a succession of letters representing a real or hypothetical DNA molecule or Sequences can be read from the biological raw material through DNA . DNA Sequencing – Real Time DNA analysis Information With the latest chellenges in DNA Sequencing, our organization looks to unravel the myths, truths and most essential assets in the deconstruction of genes. DNA Sequencing The [more...]

Date: 2010-07-09 03:20:29

DNA Damage Links Mitochondrial Dysfunction to Atherosclerosis and ...

Rationale: DNA damage is present in both genomic and mitochondrial DNA in atherosclerosis. However, whether DNA damage itself promotes atherosclerosis, or is simply a byproduct of the risk factors that promote atherosclerosis, [more...]

Date: 2010-08-12 19:57:10

Biomarker Validation Aging: Lessons mtDNA Heteroplasmy Analyses Early

2173 Article Views Authors: Peter E. Barker and Mahadev Murthy Publication Date: 27 Nov 2009 Journal: Biomarker Insights 2009:4 165-179 Abstract The anticipated biological and clinical utility of biomarkers has attracted significant interest recently. Aging and early cancer detection represent areas active in the search for predictive and prognostic biomarkers. While applications differ, overlapping biological features, analytical technologies and specific biomarker analytes bear comparison. Mitochondrial DNA (mtDNA) as a biomarker in both biological models has been evaluated. However, [more...]

Date: 2009-11-27 01:47:09

Yearning for (re)animate Nature: Faunal Colonialism in ...

In the case of woolly mammoths found frozen in permafrost—which are among the best preserved specimens of extinct Pleistocene fauna—only short strands of mitochondrial DNA have been recovered—not the nuclear DNA that would be necessary for cloning (Lindahl 1999)”. Cited in Yule. (Wayne et al. also confirm the 100,000 years limit.) But in the future, as they say, it could be possible. And as an aside, We wonder when Bog’men’ Icemen, peat men etc and mummies, will be cloned, and the possible themepark/spectacular forms this may [more...]

Date: 2010-10-09 10:39:04

Dienekes' Anthropology Blog: Origin of mtDNA haplogroup H

More than a third of the European pool of human mitochondrial DNA (mtDNA) is fragmented into a number of subclades of haplogroup (hg) H, the most frequent hg throughout western Eurasia. While there has been considerable recent progress in studying mitochondrial genome variation in Europe at the complete sequence resolution, little data of comparable resolution is so far available for regions like the Caucasus and the Near and Middle East - areas where most of European genetic lineages, including hg H, have likely emerged. This gap in our knowledge causes a serious hindrance for progress in [more...]

Date: 2006-11-10 19:17:00

Using Genetic Genealogy to Discover Royal Relatives - Genealogy ...

The DNA testing revealed that Mr. Holland is a long-lost relative of a ruling family in Cameroon, West Africa. In November, Mr. Holland will take his American family, including his 79 year old mother, to Cameroon, to visit with his African family. How exciting!This is one example of how genetic genealogy can be used. Genetic genealogy looks at a select number of DNA markers, (instead of examining the entire genome, or the information used for paternity tests). In general, there are two ways to go. The company offering services in genetic genealogy may look at the Y-chromosome, which is passed [more...]

Date: 2010-09-09 18:00:24

Chernobyl: a DNA discovery on substitution rates

Chernobyl species decline linked to DNA Victoria Gill writes about the following paper: Historical mutation rates predict susceptibility to radiation in Chernobyl birds (full text PDF) written by A.P. Moller, J. Erritzoe, F. Karadas, and T.A. Mousseau affiliated with French, Norwegian, Danish, Turkish, and American institutions. They wanted to figure out which species are going to be affected by events of the Chernobyl type - that clearly increase the mutation rates etc. Which of them will see their abundance decline quickly? The answer sounds logical but it's always helpful to confirm a [more...]

Date: 2010-08-23 04:50:00

Cancer type-specific modulation of mitochondrial haplogroups in ...

Cancer type-specific modulation of mitochondrial haplogroups in breast, colorectal and thyroid cancer (BMC Cancer) Background: Mitochondrial DNA (mtDNA) haplogroups and single nucleotide polymorphisms (mtSNP) have been shown to play a role in various human conditions including aging and some neurodegenerative diseases, metabolic diseases and cancer. Methods: To investigate whether mtDNA haplogroups contribute to the occurrence of cancer in a specific Chinese population, we have carried out a comprehensive case-control study of mtDNA from large cohorts of patients with three common cancer [more...]

Date: 2010-08-12 17:59:10

ISPUB - Comparison and Development of A Rapid Extraction Methods ...

Ancient DNA: Recovery and Analysis of Genetic Material from Paleontological, Archaeological, Museum, Medical and Forensic Specimens. New York, NY: Springer Verlag. (s)7. Holland, M.M. and T.J. Parsons. 1999. Mitochondrial DNA sequence analysis— validation and use for forensic casework. Forensic Science Review. 11: 22 – 49. (s)8. Matysiak-Scholze,U., Dimmeler,S. and Nehls,M. (1996) Technical Tips Online, T40011. (s)9. Near T.J., Bolnic D.I. and Wainwright P.C., Fossil calibrations and molecular divergence time estimates in centrarchid fishes, Evolution, 2005, 59(8): 1768-1782 (s)10. Paabo [more...]

Date: 2010-06-06 01:06:13

Age Confirmed for 'Mitochondrial Eve'

The results are based on analyses of mitochondrial DNA. Found in the energy-producing centers of cells, mitochondrial DNA is only passed down the maternal line, and can be traced back to one woman. However, this doesn't mean she was the [more...]

Date: 2010-08-21 11:51:18

How Fingerprinting Helps In DNA Paternity Testing

This form of fingerprinting method is also known as DNA profiling. Using this technique, the individuals are identified on the basis of their unique DNA profiles. This DNA profiling is done by analyzing the VNTR sequences. It stands for variable number tandem repeats. This sequence is found to be different in individuals except in twins. As per the facts mentioned above, the DNA samples of the child will exhibit the similar VNTR loci as that of their parents. This fingerprinting helps in identifying that whether the known father of a child is genuinely his biological dad. In fact, it is [more...]

Date: 2010-08-09 11:41:10

KABT BioBlog | Blog | The BEN portal of the National Science ...

Mitochondrial DNA Clarifies Human Evolution : This article and associated material/lesson plan can be used to identify the structure and function of mitochondria and to understand mitochondria’s role in evolution. A Beginner’s Guide to the Study of Plant Structure : A variation of this resource can provide guidelines for conducting a laboratory exercise in botany and plant structure. Students will become familiar with the standard techniques of light microscopy, including staining, sectioning, and drawing. Resources for AP Biology Teachers: Renewable Energy Curriculum Units : The [more...]

Date: 2010-10-04 14:56:44

DNA: Size Does Matter. But is it Science or Art? « Exploratorium ...

Then I randomly found this website, which starts with the same idea as our DNA Cheek Cell Extraction Demo but takes it to a whole new level:  You send your cheek cells in the mail to their company.  They extract your DNA from your cells, then use PCR to amplify unique sections of DNA in your genome.  This DNA is loaded into a gel and a current is run through the gel to separate the DNA based on size.  UV dye is added to the whole thing to make your DNA strands visible, a photograph is taken, and voila!…a giant canvas print with the color scheme of your choice is ready to hang on your [more...]

Date: 2008-05-14 07:37:47

Examining Mitochondrial DNA Damage

Under normal growth conditions, ROS leads to a low level of mtDNA and nuclear DNA (nDNA) damage, which is rapidly repaired, and most oxidative DNA lesions are repaired by the base excision repair (BER) pathway ... The purpose of the study presented here was to determine if there is an increased mtDNA in the lens with age. ... The gene expression key BER enzymes decreased with age, which caused a decrease in the repairing capability of the mtDNA and the accumulation of mtDNA damage. The increased mtDNA damage and decreased expression of BER enzymes may cause a "vicious cycle" of [more...]

Date: 2010-09-09 03:15:50

Ancestry DNA Testing

DNA research worldwide led to the discovery of genetic markers that are used to evaluate ancestry. These markers follow three types of inheritance pattern categories. These are autosomal DNA line, the paternal DNA line and maternal DNA line. The autosomal DNA line is made of all DNA in the cells excluding the X – chromosome, Y – chromosome and mtDNA. A person inherits half of autosomal DNA from the biological mother and the other half from the biological father. The Y chromosome markers are paternally related and passed from a father to his son. They are used to trace a person’s [more...]

Date: 2010-09-25 18:36:37

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