FamilyTreeDNA.com: New Family Finder test officially launched
Tracing the Tribe is a blog about Jewish genealogy - All the developments, tools and resources you'll need to peer more closely into your family tree. Created in 2006 at JTA's request, it is now independent. As of today, FamilyTreeDNA.com's new Family Finder test has been officially launched. The new test connects family members across all ancestral lines, not only paternal or maternal. It represents a major advancement over earlier genetic genealogy tests. Everyone, regardless of gender, can now look for connections including grandparents, aunts and uncles, half siblings, and first, [more...]
Date: 2010-05-03 17:15:00
The effect of DNA signals on nucleosome formation, chromatin ...
Much of the human genome is non-coding and it seems likely that at least some of the non-coding DNA is functionally important. However, only little is known about the possible function of the bulk of the human genome. Since essentially all the nuclear DNA is packaged into chromatin, it is likely that functional effects of non-coding DNA are mediated by the chromatin structure. By making use of human genomic sequence information now available, we showed that a specific set of periodic DNA motifs (period-10 VWG/CWB) encoded in genomic DNA is predicted to influence human chromosome function. The [more...]
Date: 2010-08-25 23:15:17
How Do I dna testing ?
The IDENTIGENE complete array of services extends from paternity testing to forensic testing and family reconstruction. You can be sure that tests performed in IDENTIGENE DNA Testing Centers will be fast, accurate and confidential. IDENTIGENE DNA Paternity Testing Centers utilize an extensive laboratory process involving bar-coded DNA samples, robotics and a Laboratory Information Management System (LIMS) assuring the highest quality of service achievable in the industry. IDENTIGENE employs system controls, checks and balances to provide reliable and accurate DNA and paternity test [more...]
Date: 2010-09-23 05:59:08
Neandertal DNA and Proteins
With the completion of the Neandertal genome by the team of Dr. Svante Paabo and a closer look at their proteins by Gregory Hannon’s team at CSHL, scientists reveal incredible similarities between Neandertals and humans. Neandertals, the extinct species of what are most likely our closest relatives, lived on earth at the same time as our human ancestors but died out about 30,000 years ago. With the sequence of their genome now complete, we can compare the DNA to humans and chimpanzees to learn more about what makes humans unique as a species. The discovery of fossils is an exciting link to [more...]
Date: 2010-05-19 13:58:17
GATE 2011 Syllabus for Biotechnology | GATE 2011 Biotechnology ...
Recombinant DNA Technology: Restriction and modification enzymes; Vectors: plasmid, bacteriophage and other viral vectors, cosmids, Ti plasmid, yeast artificial chromosome; cDNA and genomic DNA library; Gene isolation; Gene cloning; Expression of cloned gene; Transposons and gene targeting; DNA labeling; DNA sequencing; Polymerase chain reactions; DNA fingerprinting; Southern and northern blotting; In-situ hybridization; RAPD; RFLP; Site-directed mutagenesis; Gene transfer technologies; Gene therapy.w w w.w a y 2 f r e s h e r s . c o m Bioinformatics: Major bioinformatics resources (NCBI, [more...]
Date: 2010-09-01 10:17:23
Introduction To DNA Microarray Technology
Here, DNA arrays have shown promising results in almost all the fields where they have been applied. This is where I think that the greatest short-term success of DNA microarray technology lies. On a longer time scale molecular biology [more...]
Date: 2010-06-08 08:08:17
describe how advances in understanding DNA have influenced the ...
Question by S**** *: describe how advances in understanding DNA have influenced the development of new technologies? Best answer: Answer by joshi by understng the DNA…….which is the basic life form………hav influenced the dev of new technologies lik…..dna micra arrays,,,,,dna sequencing. What do you think? Answer [more...]
Date: 2010-08-24 12:30:02
DNA sequencing » Blog Archive » Microarray
Find more about Microarray on Wikipedia’s sister projects: A microarray is a multiplex lab-on-a-chip. It is a 2D array on a Genome.gov | DNA Microarray Technology Fact sheet on DNA microarray technology, published by the National Human Genome Research Institute. Microarray Technology: An introduction to DNA Microarray Learn how the microarray technology works: A short tutorial that gives an introduction to the microarray technique and it’s [more...]
Date: 2010-08-19 12:26:07
Targeted sequence capture - Nimblegen + GS Junior - SEQanswers
I would like to take 40-50 primary tumors and extract genomic DNA, create a custom array chip that will capture my regions of interest (three well-characterized genes that are 50-100kb in length). Sequence these regions across all tumors and look at the genetic variation present therein. I am hoping to use a GS Junior to do the sequencing (that works right?) and they recommend NimbleGen capture arrays. Does this sound feasible?? Much [more...]
Date: 2010-10-11 22:07:19
DNA Art Design Studio
As you may have noticed, we have redesigned our website to offer new DNA art design tools, a wider array of customizable products--including customizing colors and adding a photo to your DNA Art Portrait--and an enhanced online experience. Here are a few screenshots of the custom photo upload tool and the custom color selector tool. Give them a try and let us know what you think. Yonder Biology offers personal DNA art, doggie DNA art, DNA art apparel, and personalized [more...]
Date: 2010-07-22 04:10:00
Mutation Rate In Humans Gets Measured By Direct Sequencing
With better measurements of mutation rates, we could improve the calibration of the evolutionary clock, or test ways to reduce mutations, for example. Even with the latest DNA sequencing technology, the researchers had to design a special strategy to search for the vanishingly rare mutations. They used next-generation sequencing to establish the order of letters on the two Y chromosomes and then compared these to the Y chromosome reference sequence. Having identified 23 candidate SNPs – or single letter changes in the DNA – they amplified the regions containing these candidates and [more...]
Date: 2009-08-27 14:01:30
Yonder LLC Debuts DNA Art Website
... www.yonderbiology.com, offering new DNA art design tools, a wider array of customizable product for consumers--including customizing colors and adding a photo to one's DNA Art Portrait--and an enhanced online experience. read [more...]
Date: 2010-07-23 04:00:00
dna testing kit cvs | Paternity Tests
dna testing kit cvs. December 31, 2009. How do you define DNA testing? It is specified testing that looks for the absence or presence of DNA sequences. It makes use of molecular methods like DNA chips, arrays, or polymerase chain [more...]
Date: 2009-12-31 11:13:07
ICTS Pilot Grant Recipients Forge New Ground to Identify Disease ...
DNA is a duplex, therefore the patient's DNA, labeled with a dye, will hybridize to DNA on the array. The investigators then treat the array with an enzyme called a mismatch endonuclease that will seek out and digest any places in the DNA duplexes that contain mismatches, thus identifying the mutation's location. “You take someone’s genomic DNA, chop it up, label it using a florescent dye, and hybridize it to the microarray so that complementary features on the array can bind with the labeled DNA,” explained Manak. “Treatment with the enzyme results in cleavage at the mismatches, [more...]
Date: 2010-07-22 21:40:50
Microarray Analysis and Tumor Classification — NEJM
There are two basic approaches to generating microarray data. In a two-color array, two samples of RNA, each labeled with a different dye, are simultaneously hybridized to the array (Figure 2Figure 2 Overview of DNA Microarray Analysis. [more...]
Date: 2006-06-07 20:56:39
Technology Review: A Portable DNA Detector
A new portable DNA analyzer performs real-time analysis of blood samples left at the scene of a crime. Researchers at the University of California, Berkeley, developed the device, which packs microfluidics, electronics, optics, and chemical detection technology into a single briefcase-sized unit. "While previous groups have developed lab-on-a-chip systems, none of them have succeeded in making a completely portable, robust system that can be used at a scene," says team leader Richard Mathies. On-site CSI: After a blood sample is collected from the scene of a crime, this briefcase-sized [more...]
Date: 2008-09-24 04:00:00
GenInv – Health and Wellness » Isolation of active constituents of ...
The process of carcinogenesis is the result of DNA damage that occurs in normal cell and leads towards a growth and survival advantage. Tumor produce inflammatory cytokines some are autocrine motility factor, vascular endothelial growth factor, tumor necrosis factor (TNF-alpha), interleukin-1(IL-1), interleukin-6(IL-6), stromal derived factor-1, various chemokines and cytokines. Tumor cells attract a diverse leuko cyte population for example neutrophils, macrophages, eosinophils, mast cells, lymphocytes all for example neutrophils, macrophages, eosinophils ,mast cells, lymphocytes [more...]
Date: 2010-10-12 09:00:03
Popular Mechanics Posts 2010 BREAKTHROUGH Awards — The Gadgeteer
While working at the National Institutes of Health in the early 1990s, Venter developed a way to rapidly discover genes by exploiting snippets of DNA called expressed sequence tags. In 1992, he founded The Institute for Genomic Research, and, three years later, he and a team decoded the first genome of a free-living organism. That led to Venter’s best-known breakthrough, mapping the human genome. Last May, he achieved a defining moment in the history of biology when he inserted digitally created DNA into a living bacterium, forming the first synthetic life. His ultimate goal is to design [more...]
Date: 2010-09-28 20:43:25
Progenika Receives CE Mark for First DNA Chip to Detect Mutations ...
The Leading Information Source for Chronic Disease Research and Management Metabolic Type I Diabetes Type II Diabetes Neuropathy Retinopathy Thyroid Disorder Addisons Disease Dialysis Kidney Disorders Obesity Cardiovascular Hypertension Cardiac Arrythmias Coronary Artery Disease Heart failure Angina Central Nervous System Parkinson's Disease Schizophrenia ADHD Anxiety Depression Epilepsy Obsessive Compulsive Disorder Alzheimer Dementia Fibromyalgia Lou Gehrig's Respiratory Asthma Bronchiectasis Cystic Fibrosis Chronic Obstructive Airways [more...]
Date: 2010-09-27 08:54:00
Interesting Reading #557 – Padlock death test, Death of syringes ...
Interesting Reading #557 – Padlock death test, Death of syringes, Death of depression, Death of McMansions and much more… by Marshall Brain | August 19, 2010 1 Comment | Add Comment Can Your Padlock Withstand a Bullet? Abusive Lab Test – “A padlock can be all that stands between a burglar and a shed or lockbox full of property. But how well can it really handle the tools of a determined thief (or years of bad weather, for that matter)? To find out, we enlisted the expertise of our friends at Minnesota’s Environ Labs testing facility, where we put four models—from cheap [more...]
Date: 2010-08-20 03:20:34
Genomics and Gene Sequencing IPOs Booming?
The Company was founded in 2005, has 159 employees, and has a proprietary DNA sequencing platform with integrated software and bioinformatics providing services for genomic based research (see Raygent profile). Applications for the complete genome sequencing services are cancer research, Mendelian Disease research, Rare Variant Disease research, and clinical trial optimization. The Company has raised $95.4M since inception through six VCs and 5% shareholders: Orbimed Advisors, Essex Woodlands Health Ventures, Prospect Venture Partners III, OVP Venture Partners, Enterprise Partners and [more...]
Date: 2010-10-05 04:13:00
Whiskey Tango Foxtrot Oscar: Swearing at an oath
With this definition in mind, the evil that Israel has done becomes manifest. The legislation reeks of injustice. It only applies to one subset of Israel, to the Arab minority. It is clearly targeted toward them. It is making a blanket claim that all Israeli Arabs are forthwith considered fifth columnists. By legislative fiat Israel has now declared that Arab subversion of the Jewish state is now passed down genetically, just like Mitochondrial DNA. All Arabs are guilty of treason without exception and must prove by solemn oath otherwise. The law ironically is disobedient to the rules of [more...]
Date: 2010-10-13 12:27:00
Google TV, Apple TV, iPads, a revolution of online video products ...
I am a Baby Boomer. Class of '55, I get AARP magazine, but am still reluctant to ask for the 5 percent discount a local bakery gives "seniors" over 50. I find myself reaching for my reading glasses when my smartphone rings, otherwise I can't read the caller ID and decide whether I'm in or not, and I have to hold my GPS at arm's length to find out how far from the green I am on the golf course. I've always believed myself to be a little more tech savvy than other Boomers, and I tend to be the first on my block to get the newest toys. iPhone? Got it in week 1, dumped it for a BlackBerry Storm [more...]
Date: 2010-10-13 13:01:18
Asbestos Damage – Asbestos Dust And Dna Damage
You can buy asbestos test kits in any home store inexpensively. And as a matter of fact, they are relatively easy to use. But are they providing you with reliable results? Before we get into that question, let’s have a brief look at the material asbestos and why we still need to be mindful of the environment we are living in. Asbestos occurs in nature. It is a fibrous and friable material. Friable means that it can be broken up very easily into smaller pieces with using only very little amount of pressure. On the other hand, asbestos has been used in the manufacturing process of a wide [more...]
Date: 2010-10-09 04:21:47
Genetic Testing at Walgreens – the First Wave of Personalized ...
Soon you may be able to buy genetic testing kits at your local Walgreens, Pathway Genomics announced this week. The kits include directions on how to send a sample of your saliva back to the company for testing. The initial products will include “individualized Genetic Insight™ Report for Drug Response ($79), Pre-Pregnancy Planning ($179), Health Conditions ($179) or a combination of all three ($249)” according to the company. Are these kits reliable? What do you do with the information? The reliability of such tests depends upon the depth of understanding of our genetic “blueprint” [more...]
Date: 2010-05-14 14:21:42
Berkeley Lab News Center Press Release: New Electrostatic-based ...
In a typical experiment, a microarray is prepared and mounted in a well chamber and the DNA is hybridized (a standard technique in which complementary single strands of DNA bind to form double-stranded DNA "hybrids"). A suspension of negatively-charged silica microspheres is then dispersed through gravitational sedimentation over the microarray surface, a process which takes about 20 minutes. Because the substrate or background surface of the microassay is positively charged, the silica microspheres will spread across the entire surface and adhere to it. However, on surface areas containing [more...]
Date: 2008-06-30 16:00:00
Electrostatic trap catches tiny particles - physicsworld.com
Since their invention about 40 years ago this technique has been used with great success in biophysics, helping researchers to unravel the complex elasticity and folding dynamics of DNA, for instance. But, because optical tweezers struggle to hold on to objects that are significantly smaller than the wavelength of light, they cease to work for objects that are smaller than 100 nm. Charge rather than size Now, a group at ETH Zurich has developed an alternative mechanism for trapping particles that does not suffer from the same limitation. The device works by suspending particles within an [more...]
Date: 2010-10-06 17:00:00
STG Media Corp Selected by Identigene as their Agency of Record ...
STG Media Corp Selected by Identigene as their Agency of Record TEMPE, Ariz. — Identigene, an industry leader in DNA identification testing, has chosen STG Media Corp as their Agency of Record. Identigene is a simple and reliable DNA paternity test that is currently available in 4,500 retail locations nationwide. The test includes swabs for collecting samples from inside the cheek of a child, alleged father and mother, which are then packaged and mailed to the Identigene lab in Salt Lake City. Results of the test are reported online or by mail 3-5 business days after the samples arrive at [more...]
Date: 2008-05-05 18:23:50
csirhrdg.res.in | CSIR UGC NET 2011 Life Science Syllabus 2011 ...
Analysis of RNA, DNA and proteins by one and two dimensional gel electrophoresis, Isoelectric focusing gels. Molecular cloning of DNA or RNA fragments in bacterial and eukaryotic systems. Expression of recombinant proteins using bacterial, animal and plant vectors. Isolation of specific nucleic acid sequences Generation of genomic and cDNA libraries in plasmid, phage, cosmid, BAC and YAC vectors. In vitro mutagenesis and deletion techniques, gene knock out in bacterial and eukaryotic organisms. Protein sequencing methods, detection of post translation modification of proteins. DNA [more...]
Date: 2008-06-21 07:00:00
Evolution News & Views: Does Darrel Falk's Junk DNA Argument for ...
Dr. Falk appears to be too hasty in his assumption that pseudogenes have "no function" and thereby show evidence for common ancestry. The bottom line is that the "junk" or "gibberish" DNA paradigm is being consistently overturned as time goes on, and we now know that the vast majority of our DNA has function. As one news article said when reporting on the results of the ENCODE project in 2007: The findings, from a project involving hundreds of scientists in 11 countries and detailed in 29 papers being published today, confirm growing suspicions that the stretches of 'junk DNA' flanking [more...]
Date: 2010-03-23 19:00:45
CafePress Deal of the Day | Groupon Baltimore
Most people form first impressions of a stranger by looking at his T-shirt, unless they’ve stolen a skin kernel for DNA testing. Let the shirt you wear send a marvelous message with today's Groupon: for $25, you get $50 worth of personalized T-shirts, home goods, and other products ordered online from CafePress. Shipping is not included in this deal, but you may use your Groupon's value toward shipping costs. CafePress provides an array of inventive, humorous, and customizable clothing and gifts. Trick out your torso with the undead appeal of a zombie T-shirt ($25), or channel the talents [more...]
Date: 2009-12-17 08:00:00
geek speak - Bio-Synthesis, Inc. Begins Mitochondrial DNA Testing
Bio-Synthesis, Inc. begins Mitochondrial DNA Testing or MtDNA, making it one of only a handful of labs to perfect the technology. MtDNA Testing allows Forensic scientist to get a profile from samples that are old or possibly damaged, where the usual technique may not be effective. (Media-Newswire.com) - Recently Bio-Synthesis, Inc. has begun Mitochondrial or MtDNA Testing making it one of only 4 labs in the United States who have perfected the technology and offer it commercially. This expansion has allowed for more varied test options and opens the door to new industries that may benefit [more...]
Date: 2008-12-03 09:43:00
$25 for $50 Worth of Customized T-Shirts and Gifts from CafePress ...
Most people form first impressions of a stranger by looking at his T-shirt, unless they’ve stolen a skin kernel for DNA testing. Let the shirt you wear send a marvelous message with today’s Groupon: for $25, you get $50 worth of personalized T-shirts, home goods, and other products ordered online from CafePress . Shipping is not included in this deal, but you may use your Groupon‘s value toward shipping costs. CafePress provides an array of inventive, humorous, and customizable clothing and gifts. Trick out your torso with the undead appeal of a zombie T-shirt ($25), or channel the [more...]
Date: 2010-10-06 04:39:39
Illumina to Announce Third Quarter 2010 Financial Results on ...
We provide innovative sequencing and array-based solutions for genotyping, copy number variation analysis, methylation studies, gene expression profiling, and low-multiplex analysis of DNA, RNA and protein. We also provide tools and services that are fueling advances in consumer genomics and diagnostics. Our technology and products accelerate genetic analysis research and its application, paving the way for molecular medicine and ultimately transforming healthcare. [more...]
Date: 2010-10-13 04:08:35
GMO Pundit a.k.a. David Tribe: Genome sequence of Peruvian wild ...
We provide innovative sequencing and array-based solutions for genotyping, copy number variation analysis, methylation studies, gene expression profiling, and low-multiplex analysis of DNA, RNA and protein. We also provide tools and services that are fueling advances in consumer genomics and diagnostics. Our technology and products accelerate genetic analysis research and its application, paving the way for molecular medicine and ultimately transforming [more...]
Date: 2010-09-22 23:46:00
Venture Development Center NobleGen Biosciences joins VDC
With a proof of concept in hand, startup NobleGen Biosciences is setting up at the VDC to develop and commercialize a single-molecule sequencing technology that uses arrays of solid-state nanopores and optical detection. The method comes from the lab of Amit Meller at BU and colleagues at the University of Massachusetts Medical School. Meller filed his first patents on the technology while working at Harvard. NobleGen recently licensed a patent portfolio from Harvard and BU that includes additional IP from Meller’s research at BU. The company is led by CEO Frank Feist and Phil Buzby, former [more...]
Date: 2010-10-06 12:41:09
Low Satellite DNA Variability in Natural Populations of Drosophila ...
Low Satellite DNA Variability in Natural Populations of Drosophila antonietae Involved in Different Evolutionary Events Fernando Faria Franco, Fabio Melo Sene and Maura Helena Manfrin From the Campus de Sorocaba, Universidade Federal de São Carlos, CEP 18052-780, Sorocaba, Brazil (Franco); the Departamento de Genética, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil (Sene and Manfrin); and the Departamento de Biologia, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil (Sene and [more...]
Date: 2010-05-24 09:27:37
Kinked nanopores slow DNA passage for easier sequencing
(Nanowerk News) In an innovation critical to improved DNA sequencing, a markedly slower transmission of DNA through nanopores has been achieved by a team led by Sandia National Laboratories researchers. Solid-state nanopores sculpted from silicon dioxide are generally straight, tiny tunnels more than a thousand times smaller than the diameter of a human hair. They are used as sensors to detect and characterize DNA, RNA and proteins. But these materials shoot through such holes so rapidly that sequencing the DNA passing through them, for example, is a problem. In a paper published this week [more...]
Date: 2010-08-02 15:18:18
Obtain a pointer to data inside a trend items array - CodeGuru Forums
GetHeadPosition and GetPrev are members of MFC's CList class. They return a POSITION. You can store that and use it to position yourself anywhere in the list you want. If you need a position in an array, just store the index. .... Slow Chat : Developing Multithreaded Applications, Slow Chat: C++0x, Slow Chat: Visual C++: Yesterday, Today, and Tomorrow, Windows Central, Directory Services, General Windows and DNA Programming, Windows OS Issues, Jobs, Open Positions (Jobs) [more...]
Date: 2010-10-13 14:37:52
Dna Diagnostics Centre Uk – Dna Sample Collection For All Family …
DNA Diagnostics Centre (DDC), the leading international DNA testing laboratory provides an array of DNA testing services for solicitors and advisory organisations specialising in family law and immigration. Private clients and law … Read this article: Dna Diagnostics Centre Uk – Dna Sample Collection For All Family … Legal News Blogs Celebrating the New Totnes PV Array with an Energy Fair! » Transition Culture Excel Array Formula Series 14.4: Stock Portfolio Analysis | Microsoft Excel : Tutorial, Tips, Videos and Much More Media Group Italia – Enjoy an Array of Sporting Events in [more...]
Date: 2010-09-21 09:46:13
How is a DNA microarray different that gel electrophoresis?
I know that they are both used to kind of sort DNA and whatnot, but what’s different? Best answer: Answer by _haze_ A DNA microarray (also commonly known as gene or genome chip, DNA chip, or gene array) is a collection of microscopic DNA spots, commonly representing single genes, arrayed on a solid surface by covalent attachment to a chemical matrix. DNA arrays are different from other types of microarray only in that they either measure DNA or use DNA as part of its detection system. Qualitative or quantitative measurements with DNA microarrays utilize the selective nature of DNA-DNA or [more...]
Date: 2010-07-29 20:16:32
FTDNA Family Finder test
(BUSINESS WIRE)--Family Tree DNA, the first and largest genealogical DNA testing company, today announced the launch of the Family Finder DNA test for connecting family members across all ancestral lines. The test utilizes Affymetrix’ recently launched Axiom™ genotyping technology and the GeneTitan® System to confidently match a wide range of family relationships within five generations. Family Finder represents a major advancement over earlier genealogical tests, which revealed only connections along specific paternal lines (for males) or maternal lines (males or females). [more...]
Date: 2010-05-15 07:13:00
Ultrafast EMCCD cameras point the way to faster DNA sequencing
To harness this powerful single-molecule detection modality for high-throughput DNA sequencing, each of the four nucleotides (A, C, G and T) in the target DNA has to be converted into a predefined sequence of oligonucleotides, using a technique called Circular DNA Conversion. Each pre-defined sequence is then hybridized to a self-quenching molecular beacon.In their experimental setup, the Meller team recorded DNA translocation through a 4nm pore in a SiN membrane immersed between two aqueous solutions. With the camera in place, the researchers were able to detect florescence bursts in two [more...]
Date: 2010-06-10 07:00:00