Cirrus Engineering: Service Bulletin Revisions
Although this will be plainly obvious to the mechanic doing the work (can't test the avionics if they aren't on), we decided to revise the bulletin to ensure accuracy. The 2nd example involves SB2X-77-03R1. This service bulletin was revised due to changes in effectivity. In this case, there were a couple of airplanes that we thought would be delivered prior to the arrival of parts for production, and thus were put on the Service Bulletin. The parts arrived a few days earlier than expected, and we were able to install the new parts before they delivered. So we revised the Service Bulletin to [more...]
Date: 2010-10-12 14:50:00
Consumer Reports Health Blog: Who owns your DNA?
The costs of direct-to-consumer gene tests have been falling, and for under $1000 and a cheek swab or saliva sample, you can learn about a specific trait or disease risk, or get a profile of your whole genome and what it might mean according to current science. But making these tests more readily available to consumers hit some roadblocks in the last few months, when Pathways Genomics delayed plans to market the tests in Walgreens after receiving a letter from the FDA, and the University of California at Berkeley also withdrew its plan to offer individual gene analysis of three traits to [more...]
Date: 2010-09-20 10:00:00
Genetic-testing services offer 'misleading' results | California Watch
Flickr photo by Horia Varlan Genetic-testing services that can be administered at home and sent off to a lab misinformed their customers, promising "DNA-based disease predictions" and more, according a government employee's testimony to a Congressional subcommittee Thursday. The testing services – three of which have California offices – were found giving "test results that are misleading and of little or no practical use" to fictitious profiles that the U.S. government accountability office created, Gregory Kutz of the GAO testified Thursday. The GAO purchased 10 tests from four [more...]
Date: 2010-07-28 07:05:18
Date: 2010-10-05 00:00:00
Ultrasound for the diagnosis of breast cancer » Nano Bio Technology
Al Esma Congress (European Society for Medical Oncology) course in Milan has been made a new molecule that could become a new weapon against certain forms of breast cancer. These are molecules that carry the drug directly into tumor cells. The drug, called T-DM1 consists of two components, that together make it extremely effective: Trastuzumab, a monoclonal antibody already used successfully in the fight against the form of HER2-positive breast cancer (most common in Italy), and DM1, substance known for some time but very toxic to the body and are not used in therapy. The antibody carries [more...]
Date: 2010-10-13 07:40:35
'Savior sibling' case raises decade of ethical questions | The ...
Genetic testing of embryos is done for hundreds of different types of diseases at IVF clinics and transplant centers across the country. Wagner has recently pioneered "savior sibling" bone marrow transplants for children with a type of genetic skin disease, and he's finding that the transplanted marrow cells are capable of making new skin. He's encountered a number of cases that have made him uneasy and, he said, make the case for regulation and oversight of IVF clinics and transplant centers. One of his patients, for example, had four embryos implanted in her uterus because the testing for [more...]
Date: 2010-10-11 04:00:00
DNA findings point to royal roots in African nations
Holland attributes his success to GeneTree, a Utah-based DNA testing service that came up with the Cameroon connection. But GeneTree's chief scientific officer, geneticist Scott Woodward, said Williams' case was far from unusual. "This isn't our home run," Woodward told me. "It takes a lot of regular work. But what did do was give us some nice clues and hints about where he should concentrate his efforts. Should he be looking in Cameroon, or should he be looking in Nigeria? That makes a big difference." In fact, previous genetic tests had indeed suggested that Holland's [more...]
Date: 2010-09-09 14:14:55
A-Infos (en) Britain, Solidarity Federation Catalyst* #24 Summer ...
You don't pay tax on cash-in-hand jobs and it doesn't affect your benefits. Hence, there are more people working in domestic service than in Edwardian times, and single parents in particular are amongst those often forced to work “illegally .” .... Atos's doctors tells them to apply the harshest possible interpretation to the test. For example, the handbook says that if a claimant's memory is not so bad that he forgets to get dressed in the morning, he cannot really [more...]
Date: 2010-09-25 08:41:17
Test your DNS server performance for free, Browse the Web Faster ...
The Domain Name System (DNS) is a hierarchical naming system for computers, services, or any resource connected to the Internet or a private network. It associates various information with domain names assigned to each of the participants. Most importantly, it translates domain names meaningful to humans into the numerical (binary) identifiers associated with networking equipment for the purpose of locating and addressing these devices worldwide. An often-used analogy to explain the Domain Name System is that it serves as the "phone book" for the Internet by translating human-friendly [more...]
Date: 2010-06-14 18:21:50
LensRentals.com - How to Shoot with Wide Aperture Lenses
For example a 35mm f/1.4 on a full frame camera has a depth of field of 9 inches when focused 6 feet away, a 3 foot depth of field when focused 12 feet away, and a 21 foot depth of field when focused 30 feet away. ... If you can't find out online, test by shooting the same target at widest aperture; f/1.4; f/1.8; f/2.2; and f/2.8. If focus changes then focus shift is present. Plan to shoot either wide open or stopped down, not in between. Before going out shooting, [more...]
Date: 2010-10-13 06:59:11
Genetic Testing Firm Pathway Genomics To Sell In Walgreens ...
In another example of genetic testing's promise, small diagnostic firm XDx's AlloMap worked as well as the commonly used biopsy in testing heart transplant patients. Read More Pathway Genomics has a low-cost model of self-serve genetic testing. Go to the company's website, order a test kit that's mailed to you, and, when it arrives, just spit in a test tube enclosed in the package and send it back to Pathway's labs. Think of it as the Netflix of genetic testing. Now the company is going to get a lot more exposure through a traditional marketing approach. Walgreen Co. will begin selling [more...]
Date: 2010-05-11 14:54:00
Date: 2010-10-13 09:51:21
Polish Genetics and Anthropology Blog: My top (European) genome ...
MDS/PCA plots and inferred ancestry tests are great for uncovering the various ancestral components that make up your genome, but they won't necessarily show who your best overall genetic matches are within the project. For that sort of thing it's necessary to run pairwise comparisons between individuals based on genome-wide Identity by State/Descent (IBS/IBD) sharing. Below are my IBS results, showing my top 20 matches from the Eurogenes 500K BGA Project. The first set is based on 500,000 SNPs, with 30,000+ markers removed during quality control (for example, due to poor call rates). The [more...]
Date: 2010-09-23 07:40:00
Times' Alzheimer's test story criticized for selective statistics ...
New York Times' article on Alzheimer's disease study chastised by medical journalism critics for ignoring statistical flaws in research. By Merrill Goozner HealthNewsReview.org gave Gina Kolata's front-page New York Times story touting spinal taps to predict Alzheimer's disease a two-star rating — out of five. Chief complaint: its 100 accuracy claim ignored the test's "specificity" problem. Over a third of people told they were on the road to dementia didn't develop the disease. I'm glad somebody blew the whistle on this latest example of hyped health care coverage that so consistently [more...]
Date: 2010-08-12 18:25:38
Tainted Confessions End Up in Long Prison Sentences - Miami ...
A recent study out of the University of Virginia revealed that in 250 rape and murder cases where the defendants were eventually exonerated as a result of DNA testing, 40 individuals had confessed to a crime or crimes they did not commit. Three examples of recently exonerated, wrongfully accused defendants convicted of violent crimes come out of Broward County. Don't kid yourself, defendants charged in Miami-Dade County and across the State of Florida are doing hard time for crimes they did not commit. The lucky defendants are the ones that are released because DNA existed to prove their [more...]
Date: 2010-10-06 14:29:15
Identigene DNA Paternity Kit: Changing Families One Swab at a Time ...
Last month, I reported on the national availability of at-home DNA Paternity tests at Rite Aid pharmacies. Well, looks like the affordable kit has already been changing lives. Take Suliemon Clemens of Philadelphia, for example. Two weeks ago, Clemens wanted his twins to know that he was their father. He hadn't seen them in 14 years: "I remembered these twins when they were toddlers, and I was amazed at how they had grown up," said Clemens. "I told their mom, I just believe the children need to know the truth." As a result, Clemens marched on in to his local Rite Aid, and the lab results [more...]
Date: 2008-04-22 16:31:34
Date: 2010-10-13 10:14:52
How to Succeed as a Abap Developer or Sap Abap Development Manager ...
How to Succeed as a Abap Developer or Sap Abap Development Manager what is career development cycle Successful & Resourceful SAP ABAP Developer I have the privilege of being a ABAP developer for past 9 years and IT industry as a programmer for 12 years and now being a ABAP technical expert and development manager for 12 SAP implementations, I have come across different working patterns of a professional ABAP developer. During this time I have met a few ABAP programmers that were very good with technical aspects and also some that were excellent ABAP development consultants who could manage [more...]
Date: 2010-10-12 04:35:10
ISPUB - What's There In Our Genes? A Case For A More Inclusive And ...
We need better reviews, use of both qualitative and quantitative data as well as much more rigorous testing of newer and older models. Only then may we make full use of this large amount of data that has already been collected over the years. What we have described here, for now, presents part of the picture seen from the Indian subcontinent as an example. However, this situation is probably true of other parts of the world as well, perhaps even those areas where it has been assumed that the data is likely to be homogenous. Thus, even biological anthropologists need to add new sensitivities [more...]
Date: 2010-10-07 04:39:48
Expressing, purifying and characterizing proteins : PSI-Nature ...
Generally, the use of affinity tags to drive protein purification is widespread within PSI centers. Many tags can be used, but most groups use an N-terminal hexahistidine tag, partly because evidence suggests that hexahistidine tags do not normally have much effect on the N-terminal structure 4 and partly because histidine tags are small compared with other tags and less likely to affect solubility. An alternative for integral membrane proteins is to add a specific membrane-integrating fusion sequence for translation of integral membrane construct (Mistic); such fusions are proving useful for [more...]
Date: 2010-06-16 07:00:00
Nobel season '10: Chemistry
I've also seen that different large-scale DNA-sequencing approaches, primarily shotgun sequencing, are on the map in Swedish media which I think is really strange. Firstly because Fred Sanger, who developed shotgun sequencing, is 92 years old and a double Nobel laureate in chemistry already (1958 and 1980), and secondly because the field of large-scale sequencing still hasn't peaked by any means. Perhaps Leroy Hood (again) could be considered for the development of the first automated DNA sequencer? Anyway, the technologies that are advancing the field have been developed by private companies [more...]
Date: 2010-10-06 07:00:00
Extending Integration Services with the Script Task and Script ...
In case the required functionality doesn’t exist, there are two choices available: implement a custom component, or implement a script. Implementing a script should be easy, and that is exactly what the Script task is all about. An example of scripting using the built-in Script task I will demonstrate the functionality of the Integration Services Script task by retrieving a list of remote files from an FTP server. This functionality is currently missing in the standard FTP task, even though the FTP connection manager supports it. The Script task will require the following [more...]
Date: 2010-10-13 13:49:45
How The Environment Plays A Role In Learning | World News Today
For instance, certain individuals may be brought up in the same culture, come from the same income bracket, they may like the same leisure activities and score the same results in an IQ test but one may still be more knowledgeable than the other. This is because every individual has their own uniqueness and they respond differently to different environments. (Wood, 1998) Some environments may enhance learning experiences in comparison to others. For instance, environments in which there are many knowledgeable people normally encourage others to want to learn more about them. Therefore, such [more...]
Date: 2010-10-13 16:42:05
Pleiotropy: Some more junk DNA shown to have function
It shows a function for some "junk DNA" - DNA that does not serve any function for the developing organisms - namely in coding for micropeptides (very short proteins), which have now been shown to have a regulatory function in Drosophila. The first lines of the abstract readsA substantial proportion of eukaryotic transcripts are considered to be noncoding RNAs because they contain only short open reading frames (sORFs). Recent findings suggest, however, that some sORFs encode small bioactive peptides. Here, we show that peptides of 11 to 32 amino acids encoded by the polished rice (pri) sORF [more...]
Date: 2010-07-19 07:00:00
VTT Prints Hemoglobin Test on Paper - Kansas City infoZine News
Printed paper test can be used to test quickly and easily for the presence of a given substance. The test can be adapted to different purposes by exchanging the identifying antibody printed on the paper for another, for example. The test's subject may be many different types of liquid or substances soluble in water. Hemoglobin tests printed on paper, the left half of which indicates that the sample does not contain detectable amounts of hemoglobin. Two bars running across the right side of the test means the sample does contain a detectable amount of hemoglobin. The paper can be [more...]
Date: 2010-10-12 12:40:02
Meet Your Winemaker: Lynmar's Bibiana González Rave on Gut ...
They say it is very rare your DNA comes from one single specific region, because we are all from many places. Being Columbian, I have always thought I was American Indian blended with Spanish. But that test said I was 100% from France... an area outside Paris. My family never knew we had French roots. SI: That's pretty amazing. You literally had winemaking in your genes. At the risk of being too general, what's your winemaking philosophy? BGR: So, yes. For example something that is very important for me, and is very much my French training, is being at the vineyard and really knowing what [more...]
Date: 2010-09-29 15:30:00
Date: 2010-10-13 08:02:01
PgAdmin III 1.13 - change in plugin architecture and PostGIS ...
Select the PostGIS Viewer Plugin option, and then click the feature identifier icon tool and you should see a screen that looks like this: The Outils tab has a whole slew of tools we didn't get a chance to test out. Note: you can also launch the viewer by selecting a postgis table from the schema tree. We didn't do this since most of our tables are fairly large and painful to [more...]
Date: 2010-10-11 07:16:31
Biologists Tackle Cells' Identity Crisis
The group has now developed and tested a standardized procedure for extracting DNA from cells, doing the fingerprinting and interpreting the results.“Without policing, many investigators may not be motivated to do the necessary tests.” Many researchers already use DNA fingerprinting to test their cell lines, notes Steve Oglesbee, director of the tissue-culture facility at the Lineberger Comprehensive Cancer Center of the University of North Carolina in Chapel Hill. The ATCC and other repositories have already established fingerprints for some of the most commonly used lines. "We're [more...]
Date: 2010-06-07 13:52:00
Ethics of Technology: Prenatal Testing, Abortion & Disability ...
We didn't do genetic testing due to the risks so we were certainly surprised when Carter was born with Down Syndrome. Heck I didn't even know we could have a child with Down Syndrome. Well, he needed an operation to relieve the knot in his intestines right away. In the midst of this diagnosis a doctor who I am sure thought she was being quite clever decided to download everything she knew about Down Syndrome kids. The problem was that she focused on everything negative that she could think of for us. I should have told her to leave but we were still in shock. I truly hope this new Act helps [more...]
Date: 2008-10-29 19:34:05
Who Owns Your DNA?
... that's the question posed by Consumer's Union (publishers of Consumer Reports)... which then goes on to discuss consumer gene tests and the problems with their results - barely mentioning that question of who owns our DNA. The article is an excellent overview of the problem with over-the-counter DNA testing kits, which we actually looked at several months ago when the FDA made Walgreens pull gene testing kits off their shelves. The reason they were pulled was because their accuracy can't be tested. In fact, one analysis showed that using one DNA sample, three different tests for the [more...]
Date: 2010-10-05 06:42:35
Marianne's Your Favorite Girl: I've been tagged!
I've been blogging since the days when Xanga and Livejournal were hot, and I'm notorious for getting bored with the blog and abandoning it like a Bro who got suckered into a paternity test on Maury. I guess that would annoy me if I was an avid reader of the abandoned blog. I don't plan on abandoning this one anytime soon, if you're wondering. 7. What are you OCD about? Organizing my makeup. I have so much of it and you'd think I'd forget exactly what I have, but I can list it out by product type. I'm still pissed off about my Talika Lipocils lash conditioning gel going missing. To [more...]
Date: 2010-10-09 15:14:00
The Mermaid's Tale: BIG shoes to fill!
They have launched a search for the mythical Himalayan Yeti, often known as BigFoot in the US because the Wild West mountains have also been rumoured to be inhabited by the same, or at least some, large ape-like non-human primate. Chinese researchers have been searching since the 1970s. There have been more than 400 reported sightings of the half-man, half-ape in the Shennongjia area. In the past, explorers have found inconclusive evidence that researchers claimed to be proof of Bigfoot's existence, including hair, footprints, excrement and a sleeping nest, Xinhua reported.Is there no [more...]
Date: 2010-10-11 09:00:00
Canine dna Testing, dna Extraction from Blood, What does dna Stand For
Canine dna testing is normally achieved through a small extraction of blood, hair, cheek swab or tissue sample... Tests can be done through private independent laboratories and cost from $65 up to $250 but can cost even more. The benefits can be quite amazing as we will discover later on....but first lets answer some basic questions.... What does dna stand for...? It stands for Deoxyribonucleic Acid - and is the basic foundation to all genetics. Chromosomes are made up of the Deoxyribonucleic Acid which is a double strand which divides into genes. Your dog will have from [more...]
Date: 2009-11-23 18:25:20
Government moves to oversee at-home genetic tests - Chicago ...
The FDA first signaled a possible shift in direction after another firm, Pathway Genomics, last month moved to sell genetic test kits through Walgreens drugstores. The plan was quickly shelved, but a high-profile congressional committee launched its own investigation. The tests prompting attention are not the highly specialized DNA scans ordered by physicians. Instead, these consumer-oriented offerings evaluate an individual's risk of developing various illnesses or responding variably to different medications, based on test findings. That is problematic because most of the genetic [more...]
Date: 2010-06-15 01:08:00