DNA Interactive is an educational web site resource that celebrates the 50th anniversary of the discovery of the DNA double helix structure. There are six sections to this web site: Timeline, Code, Manipulation, Genome, Applications, Implications. Each section is split into modules and has rare video interviews with scientists, 3D animations, and narrative text to present and explain DNA science. Timeline is an interactive, animated exploration of genetics and molecular biology from Gregor Mendel and early genetics to Mario Capecchi, Francis Collins and current biotechnological techniques and [more...]
Date: 2010-08-05 15:04:31
DIY DNA Sequencing At $5000 Will Determine Cancer & Heart Conditions
Stephen QuakeAs noted in Lancet, a British medical journal, Stanford bioengineer Stephen Quake has built a DNA sequencer/decoder machine that mapped his entire body - that is, the entire 2.6 billion-letter chain of his DNA down to the last chromosome. Since the cause-and-effect relationships between illnesses and genes are not necessarily Gattacaspecific, scientists have calculated statistical correlations and probabilities. For example, if you have a certain sequence in your DNA, you may be more likely to develop a specific medical condition such as heart problems or cancer. A full [more...]
Date: 2010-10-05 13:30:00
Relations, difficult and dirty tricks between the discoverers of ...
Wilkins, who is – in the back of Franklin, by some accounts – showed Watson an image taken by his colleague, now immortalized as the picture 51, which clearly shows a double helix, an indication of the shape of DNA perceived by the young American. Alex Gann and Jan Witkowski, the two scientists who found the lost letters, say in Nature that Wilkins was a “torture”, torn between his desire to cooperate and his desire for a career and get results. Born deaf cats see better, an example of reorganization of brainPollution in Hungary: masks and goggles requiredAlzheimer's: a group of [more...]
Date: 2010-09-30 08:17:34
Witness The World's First Double Helix Bridge In Sunny Singapore
Designed to resemble the helicoidal structure of human DNA, the structure has been built almost entirely out of corrosion-free stainless steel that also features state-of-the-art computer controlled mood lighting once dusk sets in. Built according to the vision of the Australian company Cox Group, Singapore’s own Architects 61 and engineering outfit Arup the structure also features nearly 2,250 metre long steel tubes winding in opposing directions. The connection with DNA is also denoted from the two pairs of letters that appear in green and red on the bridge facade once the sun goes down. [more...]
Date: 2010-10-11 09:36:54
DNA art imitates life: Construction of a nanoscale Mobius strip
The circulations of earth's warmer and cooler ocean currents for example, describe a Möbius shape. Other topological structures are common to biological systems, particularly in the case of DNA, the 3 billion chemical bases of which are packed by the chromosome inside the cell, using topological structures. "In bacteria, plasmid DNA is wound into a supercoil," Yan explains. "Then the enzymes can come in and cut and reconfigure the topology to relieve the torsion in the supercoil so that all the other cellular machinery can have access to the gene for replication, transcription and so [more...]
Date: 2010-10-08 21:50:00
How the Most Influential Scientists Alive Today Unraveled the ...
DNA has been extensively researched by scientists wishing to further understand the complex way in which life is biochemically formed. DNA contains the genetic information that composes nearly all living organisms. In the early 1950s, molecular biologist James D. Watson led his team of researchers to the ground breaking discovery that DNA is a double-stranded chain, also referred to as a double helix. Using models, he showed how matching nucleotide base pairs from the two DNA strands interlocked to form a double helix. He then showed how the strands separate during replication, and how each [more...]
Date: 2010-09-23 10:31:56
WHATAQUEEN.COM - Timeline of United States discoveries | Move Over ...
In 1953, based on X-ray diffraction images and the information that the bases were paired, James D. Watson along with Francis Crick discovered what is now widely accepted as the first accurate double-helix model of DNA structure. ..... National Inventors Hall of Fame Science and technology in the United States Technological and industrial history of the United States Timeline of United States inventions. United States Patent and Trademark Office Yankee ingenuity [more...]
Date: 2010-10-11 20:14:30
Syyn Labs' Glowing DNA - Hack a Day
This beautiful music syncronized double helix was made by Syyn labs. Last time we saw them, they had created that amazing rube goldberg style music video for OK Go. This 100 foot long LED DNA strand took over 1000 combined man hours to build. It took 512 LEDs, 32 LED controllers, 4 Arduinos, 4 computers, over a mile of wire and a very dedicated team, which included . It takes input from beatmatching/VU software as well as a 32 button console or an iPad. You can catch a video of it in action after the break, and they plan on releasing a timelapse of the build in the near [more...]
Date: 2010-10-06 14:29:27
» Letters Reveal Rivalries in Discovery of DNA Structure ...
The British researchers wanted desperately to find the DNA structure before Pauling–but not enough to collaborate with each other. A description of some of what the newly found letters reveal is at http://nyti.ms/c4GAfh. An article in the journal Nature (http://bit.ly/bIMWXO) by the discoverers of the letters provides more information and some facsimile copies. Though much has already been written about the discovery of DNA, letters from and to someone who was instrumental in the original discovery can serve as excellent pedagogical tools. The fact that scientists share the rivalries and [more...]
Date: 2010-10-03 16:24:41
DNA Structure & Testing : How to Make a DNA Model
Making a DNA model, which is in the form of a double helix, requires using four colors to represent adenine, guanine, cytosine and thymine, the four bases that make up the genetic material. Make a DNA model to better understand it with information from a biology teacher in this free video on science. Expert: Janice Crenetti Contact: WeAreHDTV.com Bio: Janice Creneti has a Bachelor of Science in secondary science education and a Bachelor of Art in biology from Boston University. Filmmaker: Christopher [more...]
Date: 2010-09-24 11:06:06
Vector Art | Free Clip Art | Cancer Icons, Ribbon, Double Helix ...
The vector package contains 4 eps illustrator vectors of cancer icons, which include: no smoking sign, cancer ribbon, dna strand, and nucleus graphic. These vectors are usable to anyone running adobe illustrator 8 or higher. I would encourage all you good hearted designers to donate or volunteer online or at a local cancer related care center or hospital- to show the world that designers do care. For more great graphic design vector resources please check out our sponsor’s ads above. Enjoy. Click here to download Cancer Vectors Free 10 Responses to “Free Illustrator Vectors- April is [more...]
Date: 2008-04-10 04:05:17
Accessory protein function in the DNA polymerase III holoenzyme ...
The Good the Bad A special sneak preview of The Daily Double Shot's segment: The Good, the Bad and the Rad. DNA Double Helix Here is a nice view of DNA using Maya 8.0. Created using an actual DNA crystal structure from the [more...]
Date: 2010-07-26 11:53:09
Scientists Discover New Repair Mechanisme For DNA Damage
“Actually DNA is highly reactive,” Nature quoted him as saying. A number of environmental toxins and chemotherapy drugs are alkylation agents that can attack DNA. When a DNA base becomes alkylated, it forms a lesion that distorts the shape of the molecule enough to prevent successful replication. Human cells contain a single glycosylase, named AAG, that repairs alkylated bases. It is specialized to detect and delete “ethenoadenine” bases, which have been deformed by combining with highly reactive, oxidized lipids in the body. However, AAG also handles many other forms of akylation [more...]
Date: 2010-10-05 07:59:00
'Homeopathic' Signals from DNA
It is known from the very early X-ray diffraction studies of DNA that water molecules are tightly associated with the double helix, and DNA in water solution forms gels associating a large number of water molecules. [more...]
Date: 2010-08-31 12:01:01
This template with DNA double helix and molecular model will fit presentations on Polymers,powerpoint template on Polymers,template ppt on Polymers,powerpoint slide on Polymers,genetics,research, human genome, genetically engineered , recombinant, vaccine, drag, DNA, [more...]
Date: 2010-09-03 04:37:00
Science Retrospective: Who was the First to Isolate a Gene? | RNAi ...
He had the tools at his fingertips – the strains of transduced lac, a reliable exonuclease, and a method of separating and purifying each DNA strand from the lambda double helix. Nevertheless, he offered the idea to Ippen who took it back to the Beckwith lab; subsequently, she was pushed aside by the aggressive members of the group. So Ihler decided to act quickly. He grew up two transducing phages each with the lac operon in opposite orientations, he separated the DNA strands using poly-UG hybridization and density equilibrium centrifugation, and then hybridized the two opposite lambda [more...]
Date: 2010-10-06 21:59:43
How is the structure of DNA similar to a spiral staircase? | http ...
The double helix structure of DNA has been compared to a spiral staircase. What components make up the sides of the staircase and what component makes up the steps? What types of bonds hold the sides together and the steps [more...]
Date: 2010-09-19 03:36:16
The leading strand is the template strand of the DNA double helix so that the replication fork moves along it in the 3' to 5' direction. This allows the new strand synthesized complementary to it to be synthesized 5' to 3' in the same [more...]
Date: 2010-06-28 03:08:46
ScienceWiz DNA Kit
Contains 172 pieces to build a double helix, graduated test tube with caps, thermometer, pipettes, filter paper, 47 chromosome puzzle pieces, a chromosome tray, eppendorf tubes, DNA extraction buffers, ink base, in well, ink quill and a [more...]
Date: 2010-07-02 13:03:54
Athens 2004 Opening Ceremony -HD- (5.DNA/Olive Tree)
The DNA hologram & the rising of the olive tree during the Opening Ceremony of the 2004 Olympic Games in Athens as broadcast in High Definition. Music: “O Patria Mia” from G.Verdi’s Aida – Maria Callas Double Helix – Nikos Kypourgos Asteri Tou Voria – Manos Hadjidakis Lyrics: “Tora peto ya tis zois to paniyiri tora peto ya tis haras mou ti yorti fegaria mou palia kenouria mou poulia diohte ton ilio ke ti mera ap’ to vouno ya na me dite na perno san astrapi ston ourano” Translation: Now I’m flying to the feast of life now I’m flying to the celebration of my joy Old moons [more...]
Date: 2010-10-09 15:11:26
MYDNA is a smart and elegant remake of the simple shelf typology but with a twist. MYDNA is a chic and contemporary storage system inspired by the DNA concept in two different ways, fist its sophisticated, organic and stylish structure in the shape of double helix and second with a metaphorical statement which establish that everything you place on its shelves define a significant part of your personal identity. Producer: Joel Escalona [more...]
Date: 2010-08-31 08:54:24
Letters of DNA hunters reveal twists - Arkansas Online
The drama that surrounded Francis Crick and James Watson’s 1953 unveiling of the structure of DNA is no secret — Watson described the heated competition between two British research groups in his best-selling book, The Double Helix. This story is only available from the Arkansas Online archives. Stories can be purchased individually for $1.95. Click the link below to search for this story in the archives. If the search doesn't yield any results, contact the Arkansas Democrat-Gazette library at (501) 378-3851 with the section, date and page information below. » Click here to search the [more...]
Date: 2010-10-03 09:00:49
New Repair Mechanism Has Been Discovered by Researchers « New ...
In 1953, the molecular structure of DNA was discovered by Watson and Francis Crick. Since then, one of the most amazing discoveries in genetic research has been the multitudes of protein machines that repair DNA. Recently, a “fundamentally new” DNA repair mechanism was discovered by researchers at Vanderbilt University! Science Daily describes it this way, “Tucked within its double-helix structure, DNA contains the chemical blueprint that guides all the processes that take place within the cell and are essential for life. Therefore, repairing damage and maintaining the integrity of [more...]
Date: 2010-10-13 08:16:14
Rivalry Among DNA Sleuths Comes Alive in Letters - 3quarksdaily
The letters were written during a 26-year period when Crick informally guided the progress of molecular biologists around the world in establishing how DNA operates in living cells. An article on the letters was published Wednesday in the journal Nature, focusing on those related to the discovery of DNA’s double helix structure in 1953. “We are really between forces that may grind all of us to pieces,” the physicist Maurice Wilkins wrote after a disastrous attempt by Crick and his colleague James D. Watson to build a model of DNA based in part on data gathered by Rosalind Franklin. [more...]
Date: 2010-10-01 11:25:46
Slowing the translocation of double-stranded DNA using a nanopore ...
It is now possible to slow and trap a single molecule of double-stranded DNA (dsDNA), by stretching it using a nanopore, smaller in diameter than the double helix, in a solid-state membrane. By applying an electric force larger than the threshold for stretching, dsDNA can be impelled through the pore. Once a current blockade associated with a translocating molecule is detected, the electric field in the pore is switched in an interval less than the translocation time to a value below the threshold for stretching. According to molecular dynamics (MD) simulations, this leaves the dsDNA [more...]
Date: 2010-09-02 17:18:59
DNA: The Secret of Life (Films For the Humanities and Sciences ...
This entertaining and educational video combines creative cinematography and breathtaking animation from the team that won the 2000 Academy Award® for special effects in the hit movie Gladiator. The video transports viewers into the amazing world of molecular biology and presents the most graphic and easily understood explanation of DNA ever produced. DNA: The Secret of Life chronicles James Watson and Francis Crick’s 1953 revolutionary scientific breakthrough—the discovery of the double helix. This 32-minute video presentation masterfully illustrates the mechanics of the DNA double [more...]
Date: 2010-09-30 06:06:42
Newly discovered DNA repair mechanism
In BER, special enzymes known as DNA glycosylases travel down the DNA molecule scanning for these lesions. When they encounter one, they break the base pair bond and flip the deformed base out of the DNA double helix. The enzyme contains a specially shaped pocket that holds the deformed base in place while detaching it without damaging the backbone. This leaves a gap (called an "abasic site") in the DNA that is repaired by another set of enzymes.Human cells contain a single glycosylase, named AAG, that repairs alkylated bases. It is specialized to detect and delete "ethenoadenine" bases, [more...]
Date: 2010-10-07 13:58:00
Basic Definitions « saydalania4ever
2) Conservative Replication According to this model, the DNA Replication process would create a brand new DNA double helix made of two daughter strands while the parental chains would stay together. 3) Dispersive Replication According to this model the Replication Process would create two DNA double-chains, each of them with parts of both parent and daughter molecules. DNA Transcription DNA transcription is a process that involves the transcribing of genetic information from DNA to RNA. The transcribed DNA message is used to produce proteins. DNA is housed within the nucleus of our cells. It [more...]
Date: 2010-10-06 17:29:14
Replication of individual DNA molecules under electronic control ...
Nanopores can be used to analyse DNA by monitoring ion currents as individual strands are captured and driven through the pore in single file by an applied voltage. Here, we show that serial replication of individual DNA templates can be achieved by DNA polymerases held at the α-haemolysin nanopore orifice. Replication is blocked in the bulk phase, and is initiated only after the DNA is captured by the nanopore. We used this method, in concert with active voltage control, to observe DNA replication catalysed by bacteriophage T7 DNA polymerase (T7DNAP) and by the Klenow fragment of DNA [more...]
Date: 2010-10-08 10:14:00
Letters shed light on bitter rivalries behind discovery of DNA ...
The new Dysfunction Network highlights social, cultural and scientific developments impacting tomorrow's family life from an optimistic pro-technology perspective. Trends include increasingly secular lives, radical medical advances and bioengineering, sweeping education reform, debates over evolution and "nature vs. nurture," and the changing character of marriage and relationships. Stay [more...]
Date: 2010-10-03 12:28:00
Soldier of Fortune 2 Double Helix (2003)
Soldier of Fortune 2 - Double Helix (2003) - Gold Edition [Full [more...]
Date: 2010-10-13 13:04:50
Xiang-Jun's Corner: Further details of the DNA story revealed by ...
I read Watson's "The Double Helix" book a while ago, and overall I am quite familiar with the DNA story. Still, I found this account fascinating: it provides a "CAST LIST" in "The search for the structure of DNA" with photos (p521); and it succinctly summarizes the relationships among the key players. In science, no other story shows more dramatically the collaborative and competitive nature among scientists working on similar projects. Franklin’s X-ray diffraction photograph 51 of B-form DNA (see figure above, from Wikipedia), with its unambiguous evidence that DNA was helical, proved [more...]
Date: 2010-10-01 03:42:00
UC Berkeley Modifies Freshmen DNA Testing Project
August 13, 2010 "Bring Your Genes to Cal", a genetic testing project by the University of California Berkeley, was meant to be an educational tool for incoming freshmen on personalized medicine, but has turned into education for the university on the politics and policy of medical testing, reported SF Gate. The project is part of an annual exercise in which the university involves new students in a common educational experience. This year's theme was personalized medicine. The Chronicle of Higher Education added that Mark Schlissel, dean of biological sciences, said he hoped the [more...]
Date: 2010-08-13 00:00:01
Medical Transcription From Home: What Is The Difference Between ...
DNA replication is the process by which one double helix of DNA is duplicated into two identical double helices which are also identical to the mother DNA. Translation is taking the RNA just made and using it to make a protein. Translation takes place after transcription of the genetic code into mRNA has been started. Translation refers to protein synthesis, in which proteins are made by reading the sequence information after the mature and processed mRNA by a ribosome. To me, transcription still refers to transcribing from a recording. But I thought you might want to find out why you’re [more...]
Date: 2010-08-05 18:01:00
can some1 help with Genetics home work? | Mountain Bike Shoes
In humans, blood type inheritance is an example of A. complete dominance. B. codominance. C. incomplete dominance. D. predominance. 5. During division in cellular reproduction, the DNA and cytoplasm of the parent cell is distributed to two A. clones. B. chromosomes. C. daughter cells. D. simplified cells. 6. Suppose you’re looking through a microscope and you see an exchange of chromosome segments between chromosome pair 7 and chromosome pair 15. This condition is an example of A. translocation. B. duplication. C. inversion. D. relocation. 7. A DNA molecule has a unique [more...]
Date: 2010-10-11 06:15:39
DNA Transcription (Advanced)
Transcription is the process by which the information in DNA is copied into messenger RNA (mRNA) for protein production. Originally created for DNA Interactive ( http://www.dnai.org ). TRANSCRIPT The Central Dogma of Molecular Biology: “DNA makes RNA makes protein” Here the process begins. Transcription factors assemble at a specific promoter region along the DNA. The length of DNA following the promoter is a gene and it contains the recipe for a protein. A mediator protein complex arrives carrying the enzyme RNA polymerase. It manoeuvres the RNA polymerase into place… inserting it with [more...]
Date: 2010-10-03 03:02:09
Wellcome Library: Tour de Francis
So consumed was Crick with his work on the helix structure of DNA that he had a model of it displayed outside his house on 19-20 Portugal Place also referred to as ‘The Golden Helix’ where he lived with his wife Odile from Autumn 1952. The helix is not double but single here, a simple symbol of Crick’s momentous discovery the previous year. It was here on 18th October 1962 that Cambridge police were allegedly called to a disturbance involving exploding firecrackers being thrown down to the street. The owners had thrown an extravagant party to celebrate being awarded the Nobel Prize for [more...]
Date: 2010-10-13 11:40:00
.ada.aimi.kisah: dna replication.ape tu?
in this chapter, there's three processes to synthesis protein from DNA. replication(DNA>DNA)> Transcription(DNA>RNA) > Translation(RNA>Protein) just focus on Eukaryotes jea tau. prokaryotes tak masuk dalam syllabus. :) replication of DNA - separation of double strands of DNA is by Helicase. and to prevent the rewinding of the strands, there is SSBp.(Single strand Binding protein) to help. - Leading strand (5' to 3') is copied by DNA Polymerase III which functioned as template for the replication. - lagging strand ( 5' to 3') is produced by DNA Polymerase III and form Okazaki Fragment. [more...]
Date: 2010-08-18 19:04:00
How Crick and Watson's DNA lab was a hive of genius - and sexism
A batch of "lost" letters written 50 years ago has cast new light on the intense and sometimes bitter rivalries behind one of the greatest achievements of the scientific age - the discovery ... Wed 29 Sep 10 from The Independent Letters show strain in DNA team Newly-found letters of British scientists behind the discovery of the structure of DNA highlight tensions around this major scientific breakthrough. Wed 29 Sep 10 from BBC News Unread correspondence of Francis Crick: New twists in double helix discovery story are uncovered The story of the double helix's discovery has a few new twists. [more...]
Date: 2010-09-29 21:46:50
Dr. Pandey “pulls off” new DNA sequencing method
The current method to sequence DNA is called gel-electrophoresis. This process is very costly and time consuming. However, Dr. Pandey and his research team have proposed a way to make DNA sequencing far easier and cheaper than the current method. For those of you scratching your heads and wondering what the purpose of DNA sequencing could possibly be, imagine in the futurew going to the doctor and getting customized medicine just for you based on your DNA. This medicine would do exactly what it needed to in order to fix your problem because it was made specifically for you and only you. [more...]
Date: 2010-09-23 17:36:11
Syyn Labs lights up Glow festival | 89.3 KPCC
Kim Nowacki/KPCC Syyn Labs' "DNA Sequencer" lights up Santa Monica's Crescent Bay Park during the "Glow" festival on Sept. 25, 2010. The yellow caution tape wasn’t much of a deterrent for people who slid under it’s flimsy border to get a closer look at the “DNA Sequencer,” one of the flashier illuminated art installations that made up Santa Monica’s sprawling Glow festival this past Saturday. By day, the piece was a tangled mess of plywood, old-school ribbon wire and Arduino programming boards. By night, the installation’s 512 individually controlled LED lights had been [more...]
Date: 2010-09-30 17:05:39
New twists in double helix discovery story are uncovered ...
Cold Spring Harbor, NY -- The story of the double helix's discovery has a few new twists. A new primary source -- a never-before-read stack of letters to and from Francis Crick, and other historical materials dating from the years 1950-76 -- has been uncovered by two professors at the Watson School of Biological Sciences at Cold Spring Harbor Laboratory (CSHL). The letters both confirm and extend current knowledge of the circumstances surrounding the epoch-making discovery of DNA's elegant double-helical structure, for which Crick, James D. Watson (now CSHL's chancellor emeritus) and Maurice [more...]
Date: 2010-10-10 04:39:02
\'Lost\' letters reveal twists in discovery of double helix
A twist of discoveryMany have argued that Franklin deserved Nobel recognition, because her experimental work revealed the double-helix structure that helped Crick and Watson build their DNA model. Even Watson suggested much later that Franklin and Wilkins should have shared a Nobel Prize in chemistry for their contributions. Franklin, who had all the photographic evidence of DNA’s double-helix structure in front of her, had dismissed the idea of a helix. That’s because she focused her attention on the clearer data from the A form of DNA, which looks less obviously like a helix than the B [more...]
Date: 2010-09-29 20:40:05
Quick Nucleic Acid Facts
Anne Marie's Chemistry BlogBy Anne Marie Helmenstine, Ph.D., Chemistry Guide | My Bio | RSSMy BioMy BlogMy ForumRSS If you're taking general chemistry, organic, or biochemistry, you'll need to understand some basic concepts about nucleic acids, the polymers used to code the genetic information of organisms. Here are some quick nucleic acid facts to get you started: Nucleic acids are the molecules that code the genetic information of organisms. The two nucleic acids used in repair, reproduction and protein synthesis are deoxyribonucleic acid (DNA, shown) and ribonucleic acid [more...]
Date: 2010-09-27 17:16:46